5-Amino-1-phenyl-3-trifluoromethyl-1H-pyrazole-4-carboxylic acid
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چکیده
منابع مشابه
5-Amino-1-phenyl-1H-pyrazole-4-carboxylic acid
In the mol-ecule of the title compound, C(10)H(9)N(3)O(2), the pyrazole ring is approximately coplanar with the amino and carboxyl groups. The phenyl group is twisted by 48.13 (3)° relative to this plane. An intra-molecular N-H⋯O hydrogen bond stabilizes the planar conformation of the mol-ecule. The mol-ecules are linked into two-dimensional sheets by two strong inter-molecular N-H⋯N and O-H⋯O ...
متن کامل5-Amino-1-phenyl-3-trifluoromethyl-1H-pyrazole-4-carboxylic acid
In the title compound, C(11)H(8)F(3)N(3)O(2), there are two mol-ecules in the asymmetric unit wherein the phenyl rings make dihedral angles of 65.3 (2) and 85.6 (2)° with the pyrazole rings. In the crystal, pairs of mol-ecules are held together by O-H⋯O hydrogen bonds between the carboxyl groups, forming a centrosymmetric dimer with an R(2) (2)(8) motif. Intra-molecular N-H⋯O inter-actions are ...
متن کامل1-Allyl-3-amino-1H-pyrazole-4-carboxylic acid
The title compound, C(7)H(9)N(3)O(2), was prepared by alkaline hydrolysis of ethyl 1-allyl-3-amino-1H-pyrazole-4-carboxyl-ate. The crystal structure is stabilized by three types of inter-molecular hydrogen bond (N-H⋯O, N-H⋯N and O-H⋯N).
متن کامل1-(4-tert-Butylbenzyl)-3-phenyl-1H-pyrazole-5-carboxylic acid
In the title compound, C(21)H(22)N(2)O(2), the mean plane of the pyrazole ring makes dihedral angles of 18.80 (12) and 77.13 (5)°, respectively, with the mean planes of the phenyl and tert-butyl-benzyl rings. The carboxylate group is inclined at 8.51 (14)° with respect to the pyrazole ring. The crystal structure displays inter-molecular O-H⋯O hydrogen bonding, generating centrosymmetric dimers.
متن کاملSynthesis and Some Reactions of 4-Benzoyl-5-Phenyl-1-(2,4,6-Trichloro Phenyl)-1H-Pyrazole-3-Carboxylic Acid
It has long been known that pyrazole and fused pyrazole compounds possess numerous chemical, biological, medicinal and agricultural applications because of their versatile biological activities appearing as antimicrobial, antiviral, antitumor, anti-inflammatory, antihistaminic, pesticidal, antifungal and antipyretic agents. On the other hand, cyclic oxalyl compounds of type 1 have been used suc...
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ژورنال
عنوان ژورنال: Acta Crystallographica Section E Structure Reports Online
سال: 2009
ISSN: 1600-5368
DOI: 10.1107/s1600536809032188